Ctsk<em2(cre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6690423)

Ctsk^{em2(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Ctsk^{em2(cre/ERT2)Smoc}
Name:	cathepsin K; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI ID:	MGI:6690423
Synonyms:	Ctsk^{em1(2A-CreERT2-WPRE-polyA)Smoc}
Gene:	Ctsk Location: Chr3:95406567-95416673 bp, + strand Genetic Position: Chr3, 40.74 cM
Alliance:	Ctsk^{em2(cre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Ctsk^{em2(cre/ERT2)Smoc} expression driven by 1 gene

Mutation details: A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the stop codon site via CRISPR/Cas9-mediated recombination. (J:238766)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ctsk (mouse) Summary of all recombinase alleles driven by Ctsk. Alliance mouse Ctsk gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Ctsk Mutation:	31 strains or lines available

References

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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