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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695205
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: anti-Trp63 (H-137; sc-8343)
Detection system: Secondary antibody
Results
Specimen 2-S1B control: embryonic day 18.5 (more )
Note: Double labeled: red - Trp63; green - Foxj1 (assay MGI:6695204).
Structure Level Pattern Image Note
TS26: trachea epithelium Present 2 S1B control Expressed in basal cell progenitors.
Specimen 2-S1B Jag1 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Foxj1 (assay MGI:6695204).
Structure Level Pattern Image Note
TS26: trachea epithelium Present 2 S1B Jag1cKO Expressed in basal cell progenitors, similar in the control.
Specimen 2-S1B Jag2 cnull: embryonic day 18.5; Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Foxj1 (assay MGI:6695204).
Structure Level Pattern Image Note
TS26: trachea epithelium Present 2 S1B Jag2cKO A significant increase in the number of prebasal cells compared with the control.
Specimen 2-S1B Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: red - Trp63; green - Foxj1 (assay MGI:6695204).
Structure Level Pattern Image Note
TS26: trachea epithelium Present 2 S1B Jag1/2cKO A significant increase in the number of prebasal cells compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory