Tg(Neurod4-cre/ERT2)D4ATahi
Transgene Detail
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Symbol: |
Tg(Neurod4-cre/ERT2)D4ATahi |
Name: |
transgene insertion D4A, Tatsumi Hirata |
MGI ID: |
MGI:6712715 |
Synonyms: |
Neurod4CreER(D4A) |
Transgene: |
Tg(Neurod4-cre/ERT2)D4ATahi Location: unknown
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Alliance: |
Tg(Neurod4-cre/ERT2)D4ATahi page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Neurod4-cre/ERT2)D4ATahi expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Neurod4 (MGI:108055) |
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Mutation details: The transgene was constructed using a genomic BAC clone RP23-55O18 encoding the mouse neurod4 gene by inserting a CreERT2 cassette at the first ATG sequence of exon2 and the loxP site in the vector backbone (pBACe3.6) was deleted by replacement with the zeocin resistance gene. The five mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (G1C) was selected by the highest recombination rate.
(J:306016)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Neurod4
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:306016 Hirata T, et al., NeuroGT: A brain atlas of neurogenic tagging CreER drivers for birthdate-based classification and manipulation of mouse neurons. Cell Rep Med. 2021 Jul; |
All: |
1 reference(s) |
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