Tg(Tcf7-EGFP,-cre/ERT2)#Held
Transgene Detail
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Symbol: |
Tg(Tcf7-EGFP,-cre/ERT2)#Held |
Name: |
transgene insertion, Werner Held |
MGI ID: |
MGI:6717277 |
Synonyms: |
Tg(Tcf7CreER-GFP)Whe |
Transgene: |
Tg(Tcf7-EGFP,-cre/ERT2)#Held Location: unknown
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Alliance: |
Tg(Tcf7-EGFP,-cre/ERT2)#Held page
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Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Tcf7-EGFP,-cre/ERT2)#Held expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Tcf7 (MGI:98507) |
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Mutation details: The transgene consisting of a bacterial artificial chromosome (BAC) containing the entire Tcf7 locus (RP23-223A11) with an EGFP-T2A-CreERT2-polyA fusion gene inserted into the endogenous translation start codon present in exon Ia of the Tcf7 locus was injected into a pronucleus of a fertilized B6 oocytes. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:305277)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Tcf7
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:305277 Pais Ferreira D, et al., Central memory CD8(+) T cells derive from stem-like Tcf7(hi) effector cells in the absence of cytotoxic differentiation. Immunity. 2020 Nov 17;53(5):985-1000.e11 |
All: |
1 reference(s) |
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