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Ift140tm1.1(cre/ERT2)Yaos
Targeted Allele Detail
Summary
Symbol: Ift140tm1.1(cre/ERT2)Yaos
Name: intraflagellar transport 140; targeted mutation 1.1, Yao Sun
MGI ID: MGI:6718291
Synonyms: Ift140-creER
Gene: Ift140  Location: Chr17:25235056-25318461 bp, + strand  Genetic Position: Chr17, 12.53 cM
Alliance: Ift140tm1.1(cre/ERT2)Yaos page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:304652
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Ift140tm1.1(cre/ERT2)Yaos expression driven by 1 gene
 
Mutation details: A T2A-cre/ERT2-P2A-LacZ and a Rox-flanked neo selection cassette were inserted into the 3' UTR of the Ift140 gene by homologous recombination in ES cells. The neo cassette was removed subsequently. (J:304652)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ift140 (mouse)
Summary of all recombinase alleles driven by Ift140.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ift140 Mutation:  71 strains or lines available
References
Original:  J:304652 Chen Y, et al., Lineage tracing of cells expressing the ciliary gene IFT140 during bone development. Dev Dyn. 2021 Apr;250(4):574-583
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory