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Sp7tm1.1(icre)Yaos
Targeted Allele Detail
Summary
Symbol: Sp7tm1.1(icre)Yaos
Name: Sp7 transcription factor 7; targeted mutation 1.1, Yao Sun
MGI ID: MGI:6718293
Synonyms: Osx-cre
Gene: Sp7  Location: Chr15:102265038-102275498 bp, - strand  Genetic Position: Chr15, 57.51 cM
Alliance: Sp7tm1.1(icre)Yaos page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:304652
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Sp7tm1.1(icre)Yaos expression driven by 1 gene
 
Mutation details: A F2A-icre was inserted into the 3' UTR of the Sp7 gene and a frt-flanked neo selection cassette was inserted into the nonconserved intron by homologous recombination in ES cells. The neo cassette was removed subsequently by Flp recombinase. (J:304652)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sp7 (mouse)
Summary of all recombinase alleles driven by Sp7.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sp7 Mutation:  21 strains or lines available
References
Original:  J:304652 Chen Y, et al., Lineage tracing of cells expressing the ciliary gene IFT140 during bone development. Dev Dyn. 2021 Apr;250(4):574-583
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory