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Trpm4tm1.1(cre)Zuf
Targeted Allele Detail
Summary
Symbol: Trpm4tm1.1(cre)Zuf
Name: transient receptor potential cation channel, subfamily M, member 4; targeted mutation 1.1, Frank Zufall
MGI ID: MGI:6718321
Synonyms: Trpm4-IRES-Cre
Gene: Trpm4  Location: Chr7:44952579-44983495 bp, - strand  Genetic Position: Chr7, 29.24 cM
Alliance: Trpm4tm1.1(cre)Zuf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:304490
Parent Cell Line:  BAC-BA1 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S/SvEv)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Trpm4tm1.1(cre)Zuf expression driven by 1 gene
 
Mutation details: An IRES-Cre-Frt-Neo-Frt was inserted after the STOP codon of the Trpm4 gene using homologous recombination. The neo cassette was removed by crossing with Flp-recombinase expressing mice. (J:304490)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Trpm4 (mouse)
Summary of all recombinase alleles driven by Trpm4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trpm4 Mutation:  59 strains or lines available
References
Original:  J:304490 Eckstein E, et al., Cyclic regulation of Trpm4 expression in female vomeronasal neurons driven by ovarian sex hormones. Mol Cell Neurosci. 2020 Jun;105:103495
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory