Zfp683tm1.1(cre,Hbegf)Kgis
Targeted Allele Detail
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| Symbol: |
Zfp683tm1.1(cre,Hbegf)Kgis |
| Name: |
zinc finger protein 683; targeted mutation 1.1, Klaas van Gisbergen |
| MGI ID: |
MGI:6718519 |
| Synonyms: |
B6-Tg(Zfp683-tdTomato-P 2A-Cre-P2A-DTR, Zfp683tm1.1(cre,DTR)Kgis |
| Gene: |
Zfp683 Location: Chr4:133781149-133786307 bp, + strand Genetic Position: Chr4, 66.5 cM
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| Alliance: |
Zfp683tm1.1(cre,Hbegf)Kgis page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:306904
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inserted expressed sequence, Null/knockout, Recombinase, Reporter) |
| Mutations: |
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Insertion, Intergenic deletion
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Zfp683tm1.1(cre,Hbegf)Kgis expresses
1 gene
Knock-in expresses:
| Organism |
Expressed Gene |
Note |
| Not Specified |
Hbegf |
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Zfp683tm1.1(cre,Hbegf)Kgis expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: Homologous recombination in ES cells targeted to insert the fluorescent protein tdTomato, cre recombinase and the diphtheria toxin receptor (DTR) separated by P2A sequences (tdTomato-P2A-Cre-P2A-DTR) into the endogenous Zfp683 locus whereby the targeting sequence replaced exons 2, 3 and 4, as well as intronic sequences of the Zfp683 gene (knockin knockout). An FRT-flanked neomycin resistance gene was also introduced. Embryonic stem cell-derived offspring were then bred with FLPO mice to remove neo selection cassette.
(J:306904)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Zfp683
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Zfp683 Mutation: |
21 strains or lines available
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| Original: |
J:306904 Behr FM, et al., Tissue-resident memory CD8(+) T cells shape local and systemic secondary T cell responses. Nat Immunol. 2020 Sep;21(9):1070-1081 |
| All: |
4 reference(s) |
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Analysis Tools
