About   Help   FAQ
Lyz2em1(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Lyz2em1(cre/ERT2)Smoc
Name: lysozyme 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:6718613
Synonyms: Lyz2-(2A-CreERT2-WPRE-pA), Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Gene: Lyz2  Location: Chr10:117113446-117118177 bp, - strand  Genetic Position: Chr10, 65.34 cM
Alliance: Lyz2em1(cre/ERT2)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Lyz2em1(cre/ERT2)Smoc expression driven by 1 gene
 
Mutation details: CRISPR/Cas9 genome editing technology was used to insert a 2A-CreERT2-WPRE-pA coexpression cassette befor the stop codon of mouse Lyz2 gene. (J:303642)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lyz2 (mouse)
Summary of all recombinase alleles driven by Lyz2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lyz2 Mutation:  40 strains or lines available
References
Original:  J:303642 Gao P, et al., E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3. Nat Commun. 2021 Feb 19;12(1):1194
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory