About   Help   FAQ
Igs2em8(KRT14-icre)Gpt
Endonuclease-mediated Allele Detail
Summary
Symbol: Igs2em8(KRT14-icre)Gpt
Name: intergenic site 2; endonuclease-mediated mutation 8, GemPharmatech Co., Ltd
MGI ID: MGI:6718926
Synonyms: H11em1Cin(hKRT14-iCre), H11-hKRT14-iCre, keratin14-Cre
Gene: Igs2  Location: unknown  Genetic Position: Chr11, Syntenic
Alliance: Igs2em8(KRT14-icre)Gpt page
Mutation
origin
Strain of Origin:  C57BL/6JGpt
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Igs2em8(KRT14-icre)Gpt expression driven by 1 gene
 
Mutation details: CRISPR-targeting introduced an icre driven by human KRT14 enhancer and promoter into Igs2 H11 docking site. (J:293217)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: KRT14 (human)
Summary of all recombinase alleles driven by KRT14.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Igs2 Mutation:  72 strains or lines available
References
Original:  J:306959 Qu H, et al., Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing. Diabetes. 2021 May;70(5):1170-1184
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory