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Glp1rtm1.1(cre)Cors
Targeted Allele Detail
Summary
Symbol: Glp1rtm1.1(cre)Cors
Name: glucagon-like peptide 1 receptor; targeted mutation 1.1, Cathrine Orskov
MGI ID: MGI:6718964
Synonyms: GLP-1r-CRE
Gene: Glp1r  Location: Chr17:31120841-31155484 bp, + strand  Genetic Position: Chr17, 15.8 cM
Alliance: Glp1rtm1.1(cre)Cors page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:302161
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (No functional change, Recombinase)
Mutation:    Insertion
 
Glp1rtm1.1(cre)Cors expression driven by 1 gene
 
Mutation details: By homologous recombination, an Internal ribosome entry site (IRES)-CRE-FRT-Neomycin-FRT cassette was inserted just downstream of the Glp1r stop codon. The generated knock-in mice were bred with a flippase (FLP)-deleter strain to remove the neomycin selection cassette. (J:302161)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Glp1r (mouse)
Summary of all recombinase alleles driven by Glp1r.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Glp1r Mutation:  49 strains or lines available
References
Original:  J:302161 Andersen DB, et al., Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice. Endocrinology. 2021 Mar 1;162(3)
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory