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Mki67tm1.1(cre/ERT2)Bsed
Targeted Allele Detail
Summary
Symbol: Mki67tm1.1(cre/ERT2)Bsed
Name: antigen identified by monoclonal antibody Ki 67; targeted mutation 1.1, Benedict Seddon
MGI ID: MGI:6718980
Synonyms: Mki67mCherry-CreERT2
Gene: Mki67  Location: Chr7:135291513-135318090 bp, - strand  Genetic Position: Chr7, 81.32 cM, cytoband F3-F5
Alliance: Mki67tm1.1(cre/ERT2)Bsed page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:301684
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mki67tm1.1(cre/ERT2)Bsed expression driven by 1 gene
 
Mutation details: The allele was generated by targeted replacement of the terminal exon 14 of the Mki67 locus with a modified exon 14 sequences with upstream FRT flanked neomycin cassette, and downstream mCherry fusion construct, IRES sequence, and CreERT2 cDNA. Mice were crossed with actin-FLPe mice to excise the neomycin selection cassette. (J:301684)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mki67 (mouse)
Summary of all recombinase alleles driven by Mki67.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mki67 Mutation:  146 strains or lines available
References
Original:  J:301684 Verheijen M, et al., Fate Mapping Quantifies the Dynamics of B Cell Development and Activation throughout Life. Cell Rep. 2020 Nov 17;33(7):108376
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory