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Gene Expression Data
Assay Details
Assay
Reference: J:231042 Yan K, et al., The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival. J Biol Chem. 2016 Feb 5;291(6):2647-63
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6719605
Gene symbol: Brpf3
Gene name: bromodomain and PHD finger containing, 3
Reporter: lacZ
Direct Detection
Results
Specimen 4B Brpf3 +/l: embryonic day 12.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS20: embryo Present Widespread 4B Brpf3+/l Widely expressed in embryo proper.
Specimen 4C Liver Brpf3 +/l: postnatal adult; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS28: liver Ambiguous 4C Liver Brpf3+/l Low to no detectable expression liver and kidney
Specimen 4C Kidney Brpf3 +/l: postnatal adult; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS28: metanephros Ambiguous 4C Kidney Brpf3+/l Low to no detectable expression liver and kidney
Specimen 4C Testis Brpf3 +/l: postnatal adult; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS28: testis Strong 4C Testis Brpf3+/l
Specimen 4C Spinal cord Brpf3 +/l: postnatal adult; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS28: spinal cord Ambiguous 4C Spinal cord Brpf3+/l
Specimen 4C Brain Brpf3 +/l: postnatal adult; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS28: brain Strong 4C Brain Brpf3+/l
Specimen 4D Brpf3 +/l: embryonic day 9.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS15: embryo Present Widespread 4D Brpf3+/l Widely expressed in embryo proper.
Specimen E9.5 not shown: embryonic day 9.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS15: ectoplacental cone Strong
TS15: yolk sac Strong
Specimen 4E (upper right): embryonic day 16.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS24: chorioallantoic placenta Strong 4E (upper right)
TS24: yolk sac Strong 4E (upper right)
Specimen 4E (lower left): embryonic day 16.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS24: chorioallantoic placenta Strong 4E (lower left)
TS24: nasal epithelium Strong 4E (lower left)
TS24: retina Strong 4E (lower left)
TS24: yolk sac Strong 4E (lower left)
Specimen 4E (lower middle): embryonic day 16.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS24: chorioallantoic placenta Strong 4E (lower middle)
TS24: lung Strong 4E (lower middle)
TS24: yolk sac Strong 4E (lower middle)
Specimen 4E (lower right): embryonic day 16.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS24: adrenal gland Strong 4E (lower right)
TS24: bladder Strong 4E (lower right)
TS24: intestine Strong 4E (lower right)
TS24: metanephros Strong 4E (lower right)
TS24: stomach Strong 4E (lower right)
TS24: testis Strong 4E (lower right)
Specimen E12.5 not shown: embryonic day 12.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS20: chorioallantoic placenta Present
TS20: lung Present
TS20: retina Present
TS20: yolk sac Present
Specimen E14.5 not shown: embryonic day 14.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS22: chorioallantoic placenta Present
TS22: lung Present
TS22: retina Present
TS22: yolk sac Present
Specimen E18.5 not shown: embryonic day 18.5; Brpf3tm1a(EUCOMM)Wtsi/Brpf3+ (more )
Structure Level Pattern Image Note
TS26: metanephros Present
TS26: testis Present
TS26: embryo Present Regionally restricted Except for kidney and testis, expression was generally low.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory