About   Help   FAQ
Scgb1a1tm1.1(icre)Fjd
Targeted Allele Detail
Summary
Symbol: Scgb1a1tm1.1(icre)Fjd
Name: secretoglobin, family 1A, member 1; targeted mutation 1.1, Franco J DeMayo
MGI ID: MGI:6720287
Synonyms: CCSPiCre, Scgb1a1-cre
Gene: Scgb1a1  Location: Chr19:9061006-9065320 bp, - strand  Genetic Position: Chr19, 6.05 cM, cytoband A
Alliance: Scgb1a1tm1.1(icre)Fjd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185603
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Scgb1a1tm1.1(icre)Fjd expression driven by 1 gene
 
Mutation details: The improved cre (icre) and FRT-flanked neomycin resistance cassette were inserted at the translation initation site. Activity was observed the majority of airway epithelial cells including the trachea, the bronchi and bronchioles. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:185603)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Scgb1a1 (mouse)
Summary of all recombinase alleles driven by Scgb1a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scgb1a1 Mutation:  29 strains or lines available
Notes
The version of this allele that contains/ does not contain the neomycin selection cassette, Scgb1a1tm1(icre)Fjd, has been analyzed.
References
Original:  J:185603 Li S, et al., Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory