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Scgb1a1tm1.1(icre)Fjd
Targeted Allele Detail
Summary
Symbol: Scgb1a1tm1.1(icre)Fjd
Name: secretoglobin, family 1A, member 1; targeted mutation 1.1, Franco J DeMayo
MGI ID: MGI:6720287
Synonyms: CCSPiCre, Scgb1a1-cre
Gene: Scgb1a1  Location: Chr19:9061006-9065320 bp, - strand  Genetic Position: Chr19, 6.05 cM, cytoband A
Alliance: Scgb1a1tm1.1(icre)Fjd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185603
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Scgb1a1tm1.1(icre)Fjd expression driven by 1 gene
 
Mutation details: The improved cre (icre) and FRT-flanked neomycin resistance cassette were inserted at the translation initation site. Activity was observed the majority of airway epithelial cells including the trachea, the bronchi and bronchioles. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:185603)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Scgb1a1 (mouse)
Summary of all recombinase alleles driven by Scgb1a1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scgb1a1 Mutation:  28 strains or lines available
Notes
The version of this allele that contains/ does not contain the neomycin selection cassette, Scgb1a1tm1(icre)Fjd, has been analyzed.
References
Original:  J:185603 Li S, et al., Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2. Development. 2012 Jul;139(14):2500-9
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory