Vim<em1(cre/ERT2)Bzsh> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6720921)

Vim^{em1(cre/ERT2)Bzsh}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Vim^{em1(cre/ERT2)Bzsh}
Name:	vimentin; endonuclease-mediated mutation 1, Bin Zhou
MGI ID:	MGI:6720921
Synonyms:	Vim-CreER
Gene:	Vim Location: Chr2:13579122-13587637 bp, + strand Genetic Position: Chr2, 10.04 cM, cytoband A2
Alliance:	Vim^{em1(cre/ERT2)Bzsh} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Vim^{em1(cre/ERT2)Bzsh} expression driven by 1 gene

Mutation details: A CreERT2 was inserted at the start codon (ATG site) via CRISPR/Cas9-mediated homologous recombination in ES cells. (J:278026)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vim (mouse) Summary of all recombinase alleles driven by Vim. Comparative matrix view of recombinase activities Alliance mouse Vim gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Vim Mutation:	40 strains or lines available

References

Original:	J:278026 Li Y, et al., Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases. Circulation. 2018 Aug 21;138(8):793-805
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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