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Postnem1(cre/ERT2)Bzsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Postnem1(cre/ERT2)Bzsh
Name: periostin, osteoblast specific factor; endonuclease-mediated mutation 1, Bin Zhou
MGI ID: MGI:6720923
Synonyms: Postn-CreER
Gene: Postn  Location: Chr3:54268530-54298458 bp, + strand  Genetic Position: Chr3, 25.46 cM
Alliance: Postnem1(cre/ERT2)Bzsh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:278026
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Postnem1(cre/ERT2)Bzsh expression driven by 1 gene
 
Mutation details: CreERT2 was inserted at the start codon (ATG site) via CRISPR/Cas9-mediated homologous recombination in ES cells. (J:278026)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Postn (mouse)
Summary of all recombinase alleles driven by Postn.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Postn Mutation:  52 strains or lines available
References
Original:  J:278026 Li Y, et al., Genetic Lineage Tracing of Nonmyocyte Population by Dual Recombinases. Circulation. 2018 Aug 21;138(8):793-805
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
09/03/2024
MGI 6.24 		The Jackson Laboratory