About   Help   FAQ
Kank1em1(dre/ERT2)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Kank1em1(dre/ERT2)Smoc
Name: KN motif and ankyrin repeat domains 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:6724264
Synonyms: Kank1-2A-DreER, Kank1-2A-DreERT2, Kank1em1(2A-DreERT2)Smoc
Gene: Kank1  Location: Chr19:25214339-25411860 bp, + strand  Genetic Position: Chr19, 20.33 cM
Alliance: Kank1em1(dre/ERT2)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Kank1em1(dre/ERT2)Smoc expression driven by 1 gene
 
Mutation details: A 2A-DreERT2 expression cassette was knocked into the Kank1 gene stop codon site via CRISPR/Cas mediated recombination. (J:238766, J:304636)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Kank1 (mouse)
Summary of all recombinase alleles driven by Kank1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kank1 Mutation:  69 strains or lines available
References
Original:  J:304636 Han X, et al., A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. 2021 Feb 2;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory