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Upk3bem1(dre)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Upk3bem1(dre)Smoc
Name: uroplakin 3B; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:6724323
Synonyms: Upk3b-Dre, Upk3bem1(Dre-Wpre-polyA)Smoc
Gene: Upk3b  Location: Chr5:136067350-136073847 bp, + strand  Genetic Position: Chr5, 75.7 cM
Alliance: Upk3bem1(dre)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Upk3bem1(dre)Smoc expression driven by 1 gene
 
Mutation details: A Dre-Wpre-polyA expression cassette was knocked into the Upk3b gene start codon site via CRISPR/Cas9 mediated recombination. (J:238766, J:304636)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Upk3b (mouse)
Summary of all recombinase alleles driven by Upk3b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Upk3b Mutation:  14 strains or lines available
References
Original:  J:304636 Han X, et al., A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. 2021 Feb 2;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory