Foxp3<em6(dre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6724543)

Foxp3^{em6(dre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Foxp3^{em6(dre/ERT2)Smoc}
Name:	forkhead box P3; endonuclease-mediated mutation 6, Shanghai Model Organisms Center
MGI ID:	MGI:6724543
Synonyms:	Foxp3-DreERT2, Foxp3^{em5(IRES-DreER)Smoc}
Gene:	Foxp3 Location: ChrX:7445915-7461482 bp, + strand Genetic Position: ChrX, 3.41 cM
Alliance:	Foxp3^{em6(dre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Foxp3^{em6(dre/ERT2)Smoc} expression driven by 1 gene

Mutation details: An IRES-DreER expression cassette was knocked into the Foxp3 gene stop codon site via CRISPR/Cas9 mediated recombination. (J:238766)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxp3 (mouse) Summary of all recombinase alleles driven by Foxp3. Alliance mouse Foxp3 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Foxp3 Mutation:	58 strains or lines available

References

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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