Hexb<em1(cre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6724577)

Hexb^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Hexb^{em1(cre/ERT2)Smoc}
Name:	hexosaminidase B; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6724577
Synonyms:	Hexb-2A-CreERT2, Hexb^{em1(T2A-CreERT2)Smoc}
Gene:	Hexb Location: Chr13:97312839-97334865 bp, - strand Genetic Position: Chr13, 50.66 cM
Alliance:	Hexb^{em1(cre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Hexb^{em1(cre/ERT2)Smoc} expression driven by 1 gene

Mutation details: T2A-CreERT2 expression cassette was knocked into the Hexb gene via CRISPR/Cas9 mediated recombination. (J:238766)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hexb (mouse) Summary of all recombinase alleles driven by Hexb. Alliance mouse Hexb gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Hexb Mutation:	91 strains or lines available

References

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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