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Tg(Cd8a-icre/ERT2,-GFP)#Daav
Transgene Detail
Summary
Symbol: Tg(Cd8a-icre/ERT2,-GFP)#Daav
Name: transgene insertion, Dario AA Vignali
MGI ID: MGI:6726258
Synonyms: E8ICreERT2.GFP
Transgene: Tg(Cd8a-icre/ERT2,-GFP)#Daav  Location: unknown  
Alliance: Tg(Cd8a-icre/ERT2,-GFP)#Daav page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Cd8a-icre/ERT2,-GFP)#Daav expression driven by 1 gene
 
Mutation detailsThe 1.6 kb core of the E8I Cd8 locus enhancer region was inserted in front of the Cd8a promoter, and iCreERT2 cDNA and an IRES-GFP-polyA cassette were inserted after the promoter to generate the transgene construct. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:299786)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd8a (mouse)
Summary of all recombinase alleles driven by Cd8a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:299786 Liu C, et al., Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity. Nat Immunol. 2020 Sep;21(9):1010-1021
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory