Tg(Cd8a-icre/ERT2,-GFP)#Daav
Transgene Detail
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Symbol: |
Tg(Cd8a-icre/ERT2,-GFP)#Daav |
Name: |
transgene insertion, Dario AA Vignali |
MGI ID: |
MGI:6726258 |
Synonyms: |
E8ICreERT2.GFP |
Transgene: |
Tg(Cd8a-icre/ERT2,-GFP)#Daav Location: unknown
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Alliance: |
Tg(Cd8a-icre/ERT2,-GFP)#Daav page
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Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Cd8a-icre/ERT2,-GFP)#Daav expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Cd8a (MGI:88346) |
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Mutation details: The 1.6 kb core of the E8I Cd8 locus enhancer region was inserted in front of the Cd8a promoter, and iCreERT2 cDNA and an IRES-GFP-polyA cassette were inserted after the promoter to generate the transgene construct. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:299786)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Cd8a
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:299786 Liu C, et al., Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity. Nat Immunol. 2020 Sep;21(9):1010-1021 |
All: |
8 reference(s) |
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