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Sox6tm1(cre)Awar
Targeted Allele Detail
Summary
Symbol: Sox6tm1(cre)Awar
Name: SRY (sex determining region Y)-box 6; targeted mutation 1, Rajeshwar Awatramani
MGI ID: MGI:6726338
Synonyms: Sox6-FSF-Cre
Gene: Sox6  Location: Chr7:115070107-115638031 bp, - strand  Genetic Position: Chr7, 61.29 cM
Alliance: Sox6tm1(cre)Awar page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:266806
Parent Cell Line:  PRX-B6N (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Conditional ready, Recombinase)
Mutation:    Insertion
 
Sox6tm1(cre)Awar expression driven by 1 gene
 
Mutation details: By homologous recombination in ES cells, FRT-STOP-Puro-FRT cassette was inserted into the intronic region between exons 2 and 3 and a NLS-Cre-polyA was inserted into the Sox6 gene in-frame to the endogenous ATG. (J:266806)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox6 (mouse)
Summary of all recombinase alleles driven by Sox6.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox6 Mutation:  60 strains or lines available
References
Original:  J:266806 Poulin JF, et al., Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches. Nat Neurosci. 2018 Sep;21(9):1260-1271
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory