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Gabra1em1(cre)Lbrl
Endonuclease-mediated Allele Detail
Summary
Symbol: Gabra1em1(cre)Lbrl
Name: gamma-aminobutyric acid type A receptor subunit alpha 1; endonuclease-mediated mutation 1, Stephen Liberles
MGI ID: MGI:6726586
Synonyms: Gabra1-ires-Cre
Gene: Gabra1  Location: Chr11:42021766-42073757 bp, - strand  Genetic Position: Chr11, 24.97 cM
Alliance: Gabra1em1(cre)Lbrl page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Gabra1em1(cre)Lbrl expression driven by 1 gene
    Using the CRISPR/Cas9 technology, ires-Cre was inserted into the 3' UTR of the mouse Gabra1 locus. (J:298576)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gabra1 (mouse)
Summary of all recombinase alleles driven by Gabra1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gabra1 Mutation:  48 strains or lines available
References
Original:  J:298576 Prescott SL, et al., An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents. Cell. 2020 Apr 30;181(3):574-589.e14
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory