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Ms4a3tm1(cre/ERT2)Smoc
Targeted Allele Detail
Summary
Symbol: Ms4a3tm1(cre/ERT2)Smoc
Name: membrane-spanning 4-domains, subfamily A, member 3; targeted mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:6726594
Synonyms: Ms4a3CreERT2
Gene: Ms4a3  Location: Chr19:11606863-11618215 bp, - strand  Genetic Position: Chr19, 8.47 cM, cytoband B
Alliance: Ms4a3tm1(cre/ERT2)Smoc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:284702
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Ms4a3tm1(cre/ERT2)Smoc expression driven by 1 gene
 
Mutation details: A Ires-CreERT2 gene fusion was inserted into t into the 3' un-translated region (3'UTR) of the Ms4a3 gene by by homologous recombination in ES cells. (J:284702)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ms4a3 (mouse)
Summary of all recombinase alleles driven by Ms4a3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ms4a3 Mutation:  17 strains or lines available
References
Original:  J:284702 Liu Z, et al., Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells. Cell. 2019 Sep 5;178(6):1509-1525.e19
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory