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Atoh7tm3(cre/ERT2)Xmu
Targeted Allele Detail
Summary
Symbol: Atoh7tm3(cre/ERT2)Xmu
Name: atonal bHLH transcription factor 7; targeted mutation 3, Xiuqian Mu
MGI ID: MGI:6727035
Synonyms: Atoh7zsGreenCreERT2
Gene: Atoh7  Location: Chr10:62935564-62937059 bp, + strand  Genetic Position: Chr10, 32.54 cM
Alliance: Atoh7tm3(cre/ERT2)Xmu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:297659
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase, Reporter)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Atoh7tm3(cre/ERT2)Xmu expression driven by 1 gene
 
Mutation details: The zsGreen-T2A-CreERT2-SV40 poly(A)-LoxP-Neo-LoxP cassette replaced Atoh7 ORF by homologous recombination in the ES cells. It is a null allele designed to express both zsGreen and CreERT2 from the Atoh7 promoter. (J:297659)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Atoh7 (mouse)
Summary of all recombinase alleles driven by Atoh7.
 

Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atoh7 Mutation:  9 strains or lines available
References
Original:  J:297659 Ge Y, et al., Two new genetically modified mouse alleles labeling distinct phases of retinal ganglion cell development by fluorescent proteins. Dev Dyn. 2020 Aug 2;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory