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Tg(VIPR2/Hspa1b-cre/ERT2)22Dlee
Transgene Detail
Summary
Symbol: Tg(VIPR2/Hspa1b-cre/ERT2)22Dlee
Name: transgene insertion 22, Daekee Lee
MGI ID: MGI:6727075
Synonyms: VIPR2-ERT2CreERT2-022
Transgene: Tg(VIPR2/Hspa1b-cre/ERT2)22Dlee  Location: unknown  
Alliance: Tg(VIPR2/Hspa1b-cre/ERT2)22Dlee page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(VIPR2/Hspa1b-cre/ERT2)22Dlee expression driven by 1 gene
 
Mutation details: A transgene consisting of hs1753 (chr7:158,888,320-158,891,362) enhancer element located in intron 4 of human VIPR2 gene subcloned into Hsp68 promoter fused with ERT2CreERT2-pA to drive expression of cre in response to tamoxifen in developing heart. A total of nine transgenic founders lines 1, 17, 20, 22, 23, 29, 30, 32, 33 were obtained. All transgenic lines showed heart-specific cre activity when bred to a cre reporter mouse. (J:297289)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: VIPR2 (human)
Summary of all recombinase alleles driven by VIPR2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:297289 Chin HJ, et al., Tamoxifen-inducible cardiac-specific Cre transgenic mouse using VIPR2 intron. Lab Anim Res. 2020;36:31
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory