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Spon1em1(cre)Csz
Endonuclease-mediated Allele Detail
Summary
Symbol: Spon1em1(cre)Csz
Name: spondin 1, (f-spondin) extracellular matrix protein; endonuclease-mediated mutation 1, Charles S Zuker
MGI ID: MGI:6728135
Synonyms: Spon1-Cre
Gene: Spon1  Location: Chr7:113365235-113642605 bp, + strand  Genetic Position: Chr7, 59.25 cM
Alliance: Spon1em1(cre)Csz page
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Spon1em1(cre)Csz expression driven by 1 gene
 
Mutation details: CRISPR/Cas genome editing technology was used to insert IRES-CrebGHpoly(A) immediately downstream of the native Spon1 stop codon. (J:293042)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Spon1 (mouse)
Summary of all recombinase alleles driven by Spon1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spon1 Mutation:  33 strains or lines available
References
Original:  J:293042 Zhang J, et al., Sour Sensing from the Tongue to the Brain. Cell. 2019 Oct 3;179(2):392-402.e15
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory