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Avpr1atm1.1(cre)Ddg
Targeted Allele Detail
Summary
Symbol: Avpr1atm1.1(cre)Ddg
Name: arginine vasopressin receptor 1A; targeted mutation 1.1, David D Ginty
MGI ID: MGI:6728137
Synonyms: Avpr1aT2a-Cre, Avpr1aT2a-Cre(deltaneo)
Gene: Avpr1a  Location: Chr10:122284404-122289357 bp, + strand  Genetic Position: Chr10, 70.36 cM, cytoband D3
Alliance: Avpr1atm1.1(cre)Ddg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:292971
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Avpr1atm1.1(cre)Ddg expression driven by 1 gene
 
Mutation details: Using standard homologous recombination techniques in embryonic stem (ES) cells, a targeting construct consisting of a T2a-Cre-TGA codon; Frt-PGK:NeoR-pA-Frt cassette was inserted immediately upstream of the stop codon in Avpr1a. The neo selection cassette was excised using a Flp-deleter strain. (J:292971)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Avpr1a (mouse)
Summary of all recombinase alleles driven by Avpr1a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Avpr1a Mutation:  35 strains or lines available
References
Original:  J:292971 Sharma N, et al., The emergence of transcriptional identity in somatosensory neurons. Nature. 2020 Jan;577(7790):392-398
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory