Tek<em2(cre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6728794)

Tek^{em2(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Tek^{em2(cre/ERT2)Smoc}
Name:	TEK receptor tyrosine kinase; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI ID:	MGI:6728794
Synonyms:	Tek2^Cre-ERT
Gene:	Tek Location: Chr4:94627526-94763213 bp, + strand Genetic Position: Chr4, 43.34 cM
Alliance:	Tek^{em2(cre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tek^{em2(cre/ERT2)Smoc} expression driven by 1 gene

A CreERT2 expression cassette was knocked into the Tek gene. (J:301144)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tek (mouse) Summary of all recombinase alleles driven by Tek. Alliance mouse Tek gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Tek Mutation:	92 strains or lines available

References

Original:	J:301144 Zhu Z, et al., Aryl Hydrocarbon Receptor in Cutaneous Vascular Endothelial Cells Restricts Psoriasis Development by Negatively Regulating Neutrophil Recruitment. J Invest Dermatol. 2020 Jun;140(6):1233-1243.e9
All:	2 reference(s)

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