Tg(Relb-cre)53Rie
Transgene Detail
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| Symbol: |
Tg(Relb-cre)53Rie |
| Name: |
transgene insertion 53, Marc Riemann |
| MGI ID: |
MGI:6729308 |
| Synonyms: |
RelbCre-Kat, Relb-Cre-P2A-Katushka |
| Transgene: |
Tg(Relb-cre)53Rie Location: unknown
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| Alliance: |
Tg(Relb-cre)53Rie page
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| Transgene Type: |
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Transgenic (Recombinase, Reporter) |
| Mutation: |
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Insertion
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Tg(Relb-cre)53Rie expression driven by
1 gene
Transgene expression driven by:
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Mutation details: The transgene consists of a bacterial artificial chromosome (BAC) of 93 kb (bMQ-258 k08) containing the complete Relb locus with 45 kb of upstream region was modified by introducing the gene coding for a Cre recombinase and Katushka, both linked by a self-cleaving P2A peptide into the first exon of the Relb gene just downstream of the translation initiation codon. Katushka (TurboFP635) is a far-red mutant of the red fluorescent protein from sea anemone Entacmaea quadricolor. Four founder mice were obtained, which transmitted the transgene to the progeny. In one of these founder lines (#53) transgene expression reflected that of endogenous Relb which was used for further study.
(J:270571, J:292655)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Relb
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:270571 Riemann M, et al., Central immune tolerance depends on crosstalk between the classical and alternative NF-kappaB pathways in medullary thymic epithelial cells. J Autoimmun. 2017 Jul;81:56-67 |
| All: |
3 reference(s) |
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Analysis Tools
