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Grprtm2(icre)Zfc
Targeted Allele Detail
Summary
Symbol: Grprtm2(icre)Zfc
Name: gastrin releasing peptide receptor; targeted mutation 2, Zhou-Feng Chen
MGI ID: MGI:6729692
Synonyms: Grpricre, Grprtm2.1(icre)Zfc
Gene: Grpr  Location: ChrX:162296900-162332673 bp, - strand  Genetic Position: ChrX, 75.63 cM
Alliance: Grprtm2(icre)Zfc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Grprtm2(icre)Zfc expression driven by 1 gene
 
Mutation detailsThe targeting vector was designed to insert an internal ribosome entry site (IRES) fused to a codon improved cre recombinase (icre), followed by a frt-flanked neomycin resistance (neo) cassette in opposite orientation, immediately downstream of the stop codon in the 3' UTR. (J:101977)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Grpr (mouse)
Summary of all recombinase alleles driven by Grpr.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grpr Mutation:  14 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory