Grpr<em2(flpo)Ygs> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6740372)

Grpr^em2(flpo)Ygs
Endonuclease-mediated Allele Detail

Summary

Symbol:	Grpr^em2(flpo)Ygs
Name:	gastrin releasing peptide receptor; endonuclease-mediated mutation 2, Yan-Gang Sun
MGI ID:	MGI:6740372
Synonyms:	GRPR-Flpo
Gene:	Grpr Location: ChrX:162296900-162332673 bp, - strand Genetic Position: ChrX, 75.63 cM
Alliance:	Grpr^em2(flpo)Ygs page

Mutation
origin

Strain of Origin:

ICR

Mutation
description

Allele Type:

Endonuclease-mediated (Recombinase)

Mutation:

Insertion

Grpr^em2(flpo)Ygs expression driven by 1 gene

Using CRISPR/Cas9 technology, a 2A-flpo cassette was inserted in the last exon of Grpr gene. (J:308660)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Grpr (mouse) Summary of all recombinase alleles driven by Grpr. Comparative matrix view of recombinase activities Alliance mouse Grpr gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Grpr Mutation:	14 strains or lines available

References

Original:	J:308660 Liu MZ, et al., Synaptic control of spinal GRPR(+) neurons by local and long-range inhibitory inputs. Proc Natl Acad Sci U S A. 2019 Dec 5;
All:	5 reference(s)

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