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Megf10tm1.1(cre)Jnk
Targeted Allele Detail
Summary
Symbol: Megf10tm1.1(cre)Jnk
Name: multiple EGF-like-domains 10; targeted mutation 1.1, Jeremy N Kay
MGI ID: MGI:6740603
Synonyms: Megf10Cre
Gene: Megf10  Location: Chr18:57266162-57430539 bp, + strand  Genetic Position: Chr18, 31.5 cM
Alliance: Megf10tm1.1(cre)Jnk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:290493
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (No functional change, Recombinase)
Mutation:    Insertion
 
Megf10tm1.1(cre)Jnk expression driven by 1 gene
 
Mutation details: A cre recombinase expression cassette was inserted at the end of the Megf10 coding exon with the two reading frames separated by a T2A sequence. The neo selection cassette was subsequently removed. (J:290493)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Megf10 (mouse)
Summary of all recombinase alleles driven by Megf10.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Megf10 Mutation:  69 strains or lines available
References
Original:  J:290493 Peng YR, et al., Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory