Arg1tm2.1(cre/ERT2)Lky
Targeted Allele Detail
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| Symbol: |
Arg1tm2.1(cre/ERT2)Lky |
| Name: |
arginase, liver; targeted mutation 2.1, Richard M Locksley |
| MGI ID: |
MGI:6754106 |
| Synonyms: |
Arg1RFP-CreERT2 |
| Gene: |
Arg1 Location: Chr10:24791105-24803368 bp, - strand Genetic Position: Chr10, 12.26 cM
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| Alliance: |
Arg1tm2.1(cre/ERT2)Lky page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:282429
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| Parent Cell Line: |
Other (see notes) (ES Cell)
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| Strain of Origin: |
C57BL/6
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| Allele Type: |
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Targeted (Inducible, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Arg1tm2.1(cre/ERT2)Lky expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Arg1 (MGI:88070) |
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Mutation details: A targeting vector containing (in order from 5' to 3') encephalomyocarditis virus IRES, tandem dimer (td) Tomato, T2A self-cleaving peptide from Thosea asigna virus, Cre recombinase fused to the estrogen receptor ligand binding domain (ER), bovine growth hormone poly(A), and a frt-flanked neomycin resistance cassette was inserted in exon 8 downstream of the endogenous stop codon. The neomycin selection cassette was excised in male mice by crossing to FLP1 expressing female.
(J:282429)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Arg1
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Arg1 Mutation: |
25 strains or lines available
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| Original: |
J:282429 Schneider C, et al., Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming. Immunity. 2019 Jun 18;50(6):1425-1438.e5 |
| All: |
2 reference(s) |
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Analysis Tools
