Krt5<em1(cre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6758024)

Krt5^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Krt5^{em1(cre/ERT2)Smoc}
Name:	keratin 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6758024
Synonyms:	Krt5-2A-CreERT2, Krt5^{em1(2A-CreERT2)Smoc}
Gene:	Krt5 Location: Chr15:101615505-101621333 bp, - strand Genetic Position: Chr15, 56.98 cM
Alliance:	Krt5^{em1(cre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Krt5^{em1(cre/ERT2)Smoc} expression driven by 1 gene

Mutation details: The 2A-CreERT2 cassette is inserted before the 3'UTR region of the Krt5 gene via CRISPR/Cas mediated recombination.. (J:238766)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt5 (mouse) Summary of all recombinase alleles driven by Krt5. Alliance mouse Krt5 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Krt5 Mutation:	13 strains or lines available

References

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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