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Lgr5em2(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Lgr5em2(cre/ERT2)Smoc
Name: leucine rich repeat containing G protein coupled receptor 5; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
MGI ID: MGI:6758028
Synonyms: Lgr5-EGFP-IRES-CreERT2, Lgr5em1(EGFP-IRES-creERT2-WPRE-polyA)Smoc
Gene: Lgr5  Location: Chr10:115286219-115423685 bp, - strand  Genetic Position: Chr10, 63.51 cM
Alliance: Lgr5em2(cre/ERT2)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Lgr5em2(cre/ERT2)Smoc expression driven by 1 gene
    A EGFP-IRES-creERT2-WPRE-polyA expression cassette was knocked into the Lgr5 gene start codon site. (J:238766)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lgr5 (mouse)
Summary of all recombinase alleles driven by Lgr5.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lgr5 Mutation:  58 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory