Nphs2<tm1(cre/ERT2)Smoc> Targeted Allele Detail MGI Mouse (MGI:6758036)

Nphs2^{tm1(cre/ERT2)Smoc}
Targeted Allele Detail

Summary

Symbol:	Nphs2^{tm1(cre/ERT2)Smoc}
Name:	nephrosis 2, podocin; targeted mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6758036
Synonyms:	Nphs2-CreERT2, Nphs2^{tm1(IRES-CreERT2)Smoc}
Gene:	Nphs2 Location: Chr1:156138297-156155605 bp, + strand Genetic Position: Chr1, 67.71 cM, cytoband G3
Alliance:	Nphs2^{tm1(cre/ERT2)Smoc} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:238766
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:

Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Nphs2^{tm1(cre/ERT2)Smoc} expression driven by 1 gene

Mutation details: An IRES-CreERT2 co-expression cassette is inserted into the 3'UTR region of the Nphs2 gene via homologous recombination. (J:238766)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nphs2 (mouse) Summary of all recombinase alleles driven by Nphs2. Alliance mouse Nphs2 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Nphs2 Mutation:	30 strains or lines available

References

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	1 reference(s)

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