Tyr<em1(cre/ERT2)Smoc> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6758073)

Tyr^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

Symbol:	Tyr^{em1(cre/ERT2)Smoc}
Name:	tyrosinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6758073
Synonyms:	Tyr-CreERT2, Tyr^{em1(CreERT2)Smoc}
Gene:	Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
Alliance:	Tyr^{em1(cre/ERT2)Smoc} page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:

Endonuclease-mediated (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tyr^{em1(cre/ERT2)Smoc} expression driven by 1 gene

Mutation details: This tamoxifen-inducible tyrosine-CreERT2 allele was generated by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of the Tyr (tyrosine) gene. (J:238766)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tyr (mouse) Summary of all recombinase alleles driven by Tyr. Alliance mouse Tyr gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Tyr Mutation:	379 strains or lines available

References

Original:	J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:	1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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