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Wt1em1(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Wt1em1(cre/ERT2)Smoc
Name: WT1 transcription factor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID: MGI:6758077
Synonyms: Wt1-CreERT2, Wt1em1(CreERT2-WPRE-pA)Smoc
Gene: Wt1  Location: Chr2:104956874-105003959 bp, + strand  Genetic Position: Chr2, 55.06 cM, cytoband E
Alliance: Wt1em1(cre/ERT2)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Wt1em1(cre/ERT2)Smoc expression driven by 1 gene
 
Mutation details: A CreERT2-WPRE-pA expression cassette was knocked into the Wt1 gene start codon site. The cre activity was observed in the epicardium of the heart and in the mesothelia overlying most visceral organs after tamoxifen induction. (J:238766)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Wt1 (mouse)
Summary of all recombinase alleles driven by Wt1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wt1 Mutation:  34 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory