Tg(tetO-ERBB2,-cre)#Mul
Transgene Detail
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Symbol: |
Tg(tetO-ERBB2,-cre)#Mul |
Name: |
transgene insertion, William Muller |
MGI ID: |
MGI:6758107 |
Synonyms: |
TetO-ERBB2FL-IRES-Cre |
Transgene: |
Tg(tetO-ERBB2,-cre)#Mul Location: unknown
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Alliance: |
Tg(tetO-ERBB2,-cre)#Mul page
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Strain of Origin: |
Not Applicable
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Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence, Recombinase) |
Inducer: |
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doxycycline/tetracycline |
Mutation: |
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Insertion
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Tg(tetO-ERBB2,-cre)#Mul expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
bacteria |
tetO |
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Mutation details: A DNA fragment containing the Tet-responsive promoter driving a full-length human ERBB2 (ERBB2FL) and cre cDNA separated by IRES was used to generate the transgene. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:296966)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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tetO
(bacteria)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:296966 Smith HW, et al., An ErbB2 splice variant lacking exon 16 drives lung carcinoma. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20139-20148 |
All: |
1 reference(s) |
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