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Tg(Gip-icre)117Jjho
Transgene Detail
Summary
Symbol: Tg(Gip-icre)117Jjho
Name: transgene insertion 117, Jens J Holst
MGI ID: MGI:6758286
Synonyms: GIP-Cre, mGIP-Cre-117
Transgene: Tg(Gip-icre)117Jjho  Location: unknown  
Alliance: Tg(Gip-icre)117Jjho page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gip-icre)117Jjho expression driven by 1 gene
 
Mutation detailsThe sequence for icre was inserted into a BAC (RP24-298N3) by recombineering techniques, replacing the sequence between the start codon in exon 2 and the stop codon in exon 6 of the mouse Gip locus. The modified BAC was purified and injected into fertilized oocytes. Three founder lines (-117, -122, and -125) were established (estimated transgene copy numbers were 1; 1, and 2). Line 117 was used in all experiments. (J:309434)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gip (mouse)
Summary of all recombinase alleles driven by Gip.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:309434 Svendsen B, et al., GLP1- and GIP-producing cells rarely overlap and differ by bombesin receptor-2 expression and responsiveness. J Endocrinol. 2016 Jan;228(1):39-48
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory