About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:278916 Maruyama K, et al., Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6758995
Gene symbol: Adgre1
Gene name: adhesion G protein-coupled receptor E1
Antibody: Anti F4/80 (BM8)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S5A/B: embryonic day 14.5 (more )
Note: Ventral side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS22: arch of aorta Present Scattered S5B merge , S5A , S5B F4/80 Sparsely coexpressed with Lyve1 (likely macrophages) on the aortic wall.
Specimen S5C: embryonic day 14.5 (more )
Note: Dorsal side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS22: heart Present Regionally restricted S5C F4/80 , S5C merge A small number of Adgre1+/Lyve1+ macrophages were identified around the sinus venosus.
Specimen S5D/E: embryonic day 14.5 (more )
Note: Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS22: visceral pericardium Present S5E merge , S5E F4/80 , S5D Sparsely coexpressed with Lyve1 in macrophages.
Specimen S5F/G: embryonic day 15.5 (more )
Note: Ventral side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS23: aorta Present Scattered S5G merge , S5F , S5G F4/80 Coexpressed with Lyve1 in macrophages.
TS23: lymphatic vessel endothelium Absent S5F , S5G F4/80 , S5G merge
Specimen S5H: embryonic day 15.5 (more )
Note: Dorsal side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS23: visceral pericardium Present Scattered S5H merge , S5H F4/80 Coexpressed with Lyve1 in macrophages.
TS23: lymphatic vessel endothelium Absent S5H merge , S5H F4/80
Specimen S5I/J: embryonic day 15.5 (more )
Note: Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS23: visceral pericardium Present Scattered S5J F4/80 , S5J merge , S5I Coexpressed with Lyve1 in macrophages.
TS23: lymphatic vessel endothelium Absent S5I , S5J F4/80 , S5J merge
Specimen S5K/L: embryonic day 16.5 (more )
Note: Ventral side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS24: aorta Present Scattered S5L merge , S5L F4/80 , S5K Coexpressed with Lyve1 in macrophages.
TS24: lymphatic vessel endothelium Absent S5L merge , S5L F4/80 , S5K
Specimen S5M: embryonic day 16.5 (more )
Note: Dorsal side. Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS24: visceral pericardium Present Scattered S5M F4/80 , S5M merge Coexpressed with Lyve1 in macrophages.
TS24: lymphatic vessel endothelium Absent S5M merge , S5M F4/80
Specimen S5N/O: embryonic day 16.5 (more )
Note: Double labeled: green - Adgre1; red - Lyve1 (assay MGI:6758952).
Structure Level Pattern Image Note
TS24: visceral pericardium Present Scattered S5O merge , S5N , S5O F4/80 Coexpressed with Lyve1 in macrophages.
TS24: lymphatic vessel endothelium Absent S5O merge , S5N , S5O F4/80
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory