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Cacna1htm2.1(cre)Glwn
Targeted Allele Detail
Summary
Symbol: Cacna1htm2.1(cre)Glwn
Name: calcium channel, voltage-dependent, T type, alpha 1H subunit; targeted mutation 2.1, Gary R Lewin
MGI ID: MGI:6759808
Synonyms: Cav3.2Cre
Gene: Cacna1h  Location: Chr17:25593259-25652759 bp, - strand  Genetic Position: Chr17, 12.53 cM
Alliance: Cacna1htm2.1(cre)Glwn page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:309445
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutation:    Insertion
 
Cacna1htm2.1(cre)Glwn expression driven by 1 gene
 
Mutation details: Targeting vectors to insert cre expression cassette after the start codon of the Cacna1h (Cav3.2) gene located at the second exon was used to generate the allele by homologous recombination in ES cells. The insertion of the cre cassettes produces a null mutation of the Cacna1h gene. The neo cassette was removed by flpe recombinase. (J:309445)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cacna1h (mouse)
Summary of all recombinase alleles driven by Cacna1h.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacna1h Mutation:  98 strains or lines available
References
Original:  J:309445 Bernal Sierra YA, et al., Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System. Front Mol Neurosci. 2017;10:70
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory