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Hoxa5em1.1(cre)Fmr
Endonuclease-mediated Allele Detail
Summary
Symbol: Hoxa5em1.1(cre)Fmr
Name: homeobox A5; endonuclease-mediated mutation 1.1, Filippo M Rijli
MGI ID: MGI:6759846
Synonyms: Hoxa5::Cre
Gene: Hoxa5  Location: Chr6:52178768-52181437 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance: Hoxa5em1.1(cre)Fmr page
Mutation
origin
Strain of Origin:  C57BL/6 x BALB/c
Mutation
description
Allele Type:    Endonuclease-mediated (Recombinase)
Mutation:    Insertion
 
Hoxa5em1.1(cre)Fmr expression driven by 1 gene
 
Mutation details: Using CRISPR/Cas9 system, a Cre-FRT-Neo-FRT cassette was inserted into the mouse Hoxa5 ATG codon. The neo cassette was excised by mating with Flpe deleted mice. (J:306314)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Hoxa5 (mouse)
Summary of all recombinase alleles driven by Hoxa5.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa5 Mutation:  28 strains or lines available
References
Original:  J:306314 Maheshwari U, et al., Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. 2020 Jun 16;31(11):107767
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory