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Tg(Zic2-cre/ERT2)1463Kln
Transgene Detail
Summary
Symbol: Tg(Zic2-cre/ERT2)1463Kln
Name: transgene insertion 1463, Rudiger Klein
MGI ID: MGI:6760602
Synonyms: Zic2creERbroad
Transgene: Tg(Zic2-cre/ERT2)1463Kln  Location: unknown  
Alliance: Tg(Zic2-cre/ERT2)1463Kln page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Zic2-cre/ERT2)1463Kln expression driven by 1 gene
 
Mutation details: The transgene was generated by a bacterial recombineering technique to insert a cre/ERT2 expression cassette containing the polyadenylation site (polyA) from the SV40 early region into the exon 1 of the mouse Zic2 gene of a BAC clone RP23-158G6 (CHORI). Two transgenic founder lines were selected and established. Line 1463 shows broader cre activity in the spinal cord with some reporter staining seen in the dorsal root ganglion. (J:284540)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Zic2 (mouse)
Summary of all recombinase alleles driven by Zic2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:284540 Paixao S, et al., Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements. Neuron. 2019 Nov 20;104(4):749-764.e6
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory