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Tg(Pitx2-cre/ERT2)#Jfm
Transgene Detail
Summary
Symbol: Tg(Pitx2-cre/ERT2)#Jfm
Name: transgene insertion, James F Martin
MGI ID: MGI:6764477
Synonyms: Pitx2cCreERT2
Transgene: Tg(Pitx2-cre/ERT2)#Jfm  Location: unknown  
Alliance: Tg(Pitx2-cre/ERT2)#Jfm page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Pitx2-cre/ERT2)#Jfm expression driven by 1 gene
 
Mutation detailsThe construct contains a 16 kilo-base-long Pitx2 mouse 129SV genomic fragment encompassing the Pitx2 promoter and 4.2 kb downstream of exon 6. A promotor-less CreERT2 cassette, including the CreERT2 coding sequence and a poly(A) tail, was cloned into the 5' region of Pitx2 exon 4. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:310646)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pitx2 (mouse)
Summary of all recombinase alleles driven by Pitx2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:310646 Kahr PC, et al., A novel transgenic Cre allele to label mouse cardiac conduction system. Dev Biol. 2021 Oct;478:163-172
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory