About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:310126 Quarta C, et al., Functional identity of hypothalamic melanocortin neurons depends on Tbx3. Nat Metab. 2019 Feb;1(2):222-235
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6766585
Gene symbol: Cartpt
Gene name: CART prepropeptide
Antibody: anti-Cart
Detection system: Secondary antibody coupled to Alexa Fluor 647
Results
Specimen S5a - control: postnatal week 12; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Pomc1-cre)16Lowl/0 (more )
Note: Conditional mutant. Double labeled: magenta - Cartpt; green - Cre reporter.
Structure Level Pattern Image Note
TS28: arcuate nucleus Present Regionally restricted S5a Cart upper , S5a Merge upper Expression is seen in neurons.
Specimen S5a - mutant: postnatal week 12; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tbx3tm3.1Moon/Tbx3tm3.1Moon, Tg(Pomc1-cre)16Lowl/0 (more )
Note: Conditional mutant. Double labeled: magenta - Cartpt; green - Cre reporter.
Structure Level Pattern Image Note
TS28: arcuate nucleus Present S5a Cart lower , S5a Merge lower Expression is seen in neurons; there are fewer expressing neurons in the mutant compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory