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Tg(Zbtb7b/CD4-cre,-CD2)#Tani
Transgene Detail
Summary
Symbol: Tg(Zbtb7b/CD4-cre,-CD2)#Tani
Name: transgene insertion, Ichiro Taniuchi
MGI ID: MGI:6784021
Synonyms: ThPOK-Cre
Transgene: Tg(Zbtb7b/CD4-cre,-CD2)#Tani  Location: unknown  
Alliance: Tg(Zbtb7b/CD4-cre,-CD2)#Tani page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Epitope tag, Recombinase)
Mutation:    Insertion
 
Tg(Zbtb7b/CD4-cre,-CD2)#Tani expression driven by 1 gene
 
Mutation detailsA 562base pair fragment of the Zbtb7b silencer sequence was inserted into a mini-transgene containing the minimal Cd4 enhancer-promoter-cre. The sequence encoding an internal ribosomal entry site and human CD2 were also inserted downstream of the cDNA cassette encoding Cre. The transgene expresses Cre specifically in the CD4 lineage. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:193392)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Zbtb7b (mouse)
Summary of all recombinase alleles driven by Zbtb7b.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:193392 Mucida D, et al., Transcriptional reprogramming of mature CD4(+) helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat Immunol. 2013 Mar;14(3):281-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory