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Nr4a2tm1(dreo)Hze
Targeted Allele Detail
Summary
Symbol: Nr4a2tm1(dreo)Hze
Name: nuclear receptor subfamily 4, group A, member 2; targeted mutation 1, Hongkui Zeng
MGI ID: MGI:6790280
Synonyms: Nr4a2-SA-IR-Dre
Gene: Nr4a2  Location: Chr2:56996845-57014018 bp, - strand  Genetic Position: Chr2, 31.66 cM
Alliance: Nr4a2tm1(dreo)Hze page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:219930
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Nr4a2tm1(dreo)Hze expression driven by 1 gene
 
Mutation details: ES cells were retargeted to insert a splice acceptor, internal ribosomal entry site, and a mammalian-optimized D6 site-specific DNA recombinase (dreo recombinase) immediately downstream of the Nr4a2 translational STOP codon. (J:219930)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nr4a2 (mouse)
Summary of all recombinase alleles driven by Nr4a2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr4a2 Mutation:  40 strains or lines available
References
Original:  J:219930 Madisen L, et al., Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance. Neuron. 2015 Mar 4;85(5):942-58
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
07/02/2024
MGI 6.13 		The Jackson Laboratory