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Krt14tm1(cre/ERT2)Akli
Targeted Allele Detail
Summary
Symbol: Krt14tm1(cre/ERT2)Akli
Name: keratin 14; targeted mutation 1, Apostolos Klinakis
MGI ID: MGI:6791378
Synonyms: Krt14CreERT2
Gene: Krt14  Location: Chr11:100093988-100098336 bp, - strand  Genetic Position: Chr11, 63.43 cM, cytoband D
Alliance: Krt14tm1(cre/ERT2)Akli page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:239882
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Krt14tm1(cre/ERT2)Akli expression driven by 1 gene
 
Mutation details: A CreERT2-loxP-NeoR-loxP cassette was inserted into Kar14 initiation codon ATG via homologous recombination in ES cells. (J:239882)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt14 (mouse)
Summary of all recombinase alleles driven by Krt14.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Krt14 Mutation:  38 strains or lines available
References
Original:  J:239882 Papafotiou G, et al., KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis. Nat Commun. 2016 Jun 20;7:11914
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory